Atorvastatin does not protect against ischemia-reperfusion damage in cholestatic rat livers
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چکیده
منابع مشابه
Atorvastatin does not protect against ischemia-reperfusion damage in cholestatic rat livers
BACKGROUND Extrahepatic cholestasis sensitizes the liver to ischemia/reperfusion (I/R) injury during surgery for perihilar cholangiocarcinoma. It is associated with pre-existent sterile inflammation, microvascular perfusion defects, and impaired energy status. Statins have been shown to protect against I/R injury in normal and steatotic mouse livers. Therefore, the hepatoprotective properties o...
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ژورنال
عنوان ژورنال: BMC Surgery
سال: 2017
ISSN: 1471-2482
DOI: 10.1186/s12893-017-0235-9